Treatment of Type 2 Diabetes in Childhood Using a Very-Low-Calorie Diet

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Treatment of type 2 diabetes in childhood using a very-low-calorie diet.

OBJECTIVE Pharmacologic agents currently approved for use in children with type 2 diabetes (metformin and insulin) are less than optimal for some patients. We evaluated the use of a ketogenic, very-low-calorie diet (VLCD) in the treatment of type 2 diabetes. RESEARCH DESIGN AND METHODS We conducted a chart review of 20 children (mean age 14.5 +/- 0.4 years) who consumed a ketogenic VLCD in th...

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Restoring normoglycaemia by use of a very low calorie diet in long- and short-duration Type 2 diabetes.

AIMS To establish whether an 8-week very-low-calorie diet could improve glycaemic control in Type 2 diabetes of long duration. METHODS A total of 29 people with Type 2 diabetes [short-duration group (diabetes duration < 4 years), n = 15; long-duration group (diabetes duration > 8 years), n = 14] completed an 8-week very-low-calorie diet, with assessments of fasting anthropometry, blood tests ...

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Very Low-Calorie Diet and 6 Months of Weight Stability in Type 2 Diabetes: Pathophysiological Changes in Responders and Nonresponders.

OBJECTIVE Type 2 diabetes mellitus (T2DM) is generally regarded as an irreversible chronic condition. Because a very low-calorie diet (VLCD) can bring about acute return to normal glucose control in some people with T2DM, this study tested the potential durability of this normalization. The underlying mechanisms were defined. RESEARCH DESIGN AND METHODS People with a T2DM duration of 0.5-23 y...

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A very low-carbohydrate, low-saturated fat diet for type 2 diabetes management: a randomized trial.

OBJECTIVE To comprehensively compare the effects of a very low-carbohydrate, high-unsaturated/low-saturated fat diet (LC) with those of a high-unrefined carbohydrate, low-fat diet (HC) on glycemic control and cardiovascular disease (CVD) risk factors in type 2 diabetes (T2DM). RESEARCH DESIGN AND METHODS Obese adults (n = 115, BMI 34.4 ± 4.2 kg/m(2), age 58 ± 7 years) with T2DM were randomize...

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Acceptability of a very‐low‐energy diet in Type 2 diabetes: patient experiences and behaviour regulation

AIMS To evaluate the acceptability of an 8-week very-low-energy diet for remission of Type 2 diabetes, and to identify barriers and facilitators of adherence and behaviour-regulation strategies used by participants in the Counterbalance study. METHODS Eighteen of 30 participants in the Counterbalance study (ISRCTN88634530) took part in semi-structured interviews. Of these, 15 participants wer...

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ژورنال

عنوان ژورنال: Diabetes Care

سال: 2004

ISSN: 0149-5992,1935-5548

DOI: 10.2337/diacare.27.2.348